Spinal Opiate Analgesia

Spinal Opiate Analgesia, Anaesthesiologie und Intensivmedizin Anaesthesiology and Intensive Care Medicine 144, ... Summary Animal studies demonstrated that the local action of opiatesin the spinal cord would produce a highly significant ...

Spinal Opiate Analgesia

The recent development of the use of spinal opiates as a rational therapy for pain rests on clear and certain experimental data. We have long known the spinal cord to be a highly complex structure. Anatomical studies of the substantia gelatinosa have repeatedly demonstrated signs of massive synaptic interaction between primary afferents, descending pathways and intrinsic neurons. Yet, to date that knowledge, insofar as clinical therapy is concerned, has permitted us only to destroy certain connections within the spinal cord in the hopes that the substrate mediating pain could be anatomically differentiated from those which mediate other function. Though cordotomies are clearly effective under certain circumstances, they suffer from the fact the spinal cord is not organized in such an anatomically discrete fashion as is often times drawn in basic medical text. Rather, functions intertwine exquisitely and specific physical interventions are no more likely to produce a specific effect than smashing of the fmgertip with a hammer will produce just a loss of the fingernail. The development of specific therapies of the spinal cord has come about by our growing aware ness of the intricate organization of the pharmacological substrates associated with specific neural function.

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Spinal Opiate Analgesia
Language: en
Pages: 150
Authors: T. L. Yaksh, H. Müller
Categories: Medical
Type: BOOK - Published: 2012-12-06 - Publisher: Springer Science & Business Media

The recent development of the use of spinal opiates as a rational therapy for pain rests on clear and certain experimental data. We have long known the spinal cord to be a highly complex structure. Anatomical studies of the substantia gelatinosa have repeatedly demonstrated signs of massive synaptic interaction between
Spinal Narcotics
Language: en
Pages: 148
Authors: Narinder Rawal, Dennis W. Coombs
Categories: Medical
Type: BOOK - Published: 2012-12-06 - Publisher: Springer Science & Business Media

One of the most exciting developments in medicine in this century has been the discovery of opioid receptors and their pharmacology. The breadth of know- edge derived from such discovery has truly changed the practice of medicine today. The acceptance by the clinicians of the research data obtained by the
Spinal Opiate Analgesia
Language: en
Pages: 60
Authors: Lars L. Gustafsson
Categories: Medical
Type: BOOK - Published: 1985 - Publisher:

Books about Spinal Opiate Analgesia
Regional Opioid Analgesia
Language: en
Pages: 640
Authors: J. de Castro, J. Meynadier, Michael Zenz
Categories: Medical
Type: BOOK - Published: 2012-12-06 - Publisher: Springer Science & Business Media

by E.K. ZSIGMOND, M.D. Department of Anesthesiology University of Illinois Chicago U.S.A. It is, indeed, a distinct honor and privilege to be invited by the authors to write a preface to this monumental monograph, Regional Opioid Analgesia. Regional Opioid Analgesia is a colossal undertaking by Drs. De Castro, Meynadier and
Thesis spinal opiate analgesia
Language: en
Pages:
Authors: Lars L Gustafsson
Categories: Medical
Type: BOOK - Published: 1985 - Publisher:

Books about Thesis spinal opiate analgesia