Free Radical Damage and its Control

This book provides a comprehensive treatise on the chemical and biochemical consequences of damaging free radical reactions, the implications for the pathogenesis of disease and how this might be controlled endogenously and by radical ...

Free Radical Damage and its Control

This book provides a comprehensive treatise on the chemical and biochemical consequences of damaging free radical reactions, the implications for the pathogenesis of disease and how this might be controlled endogenously and by radical scavenging drugs. Oxidative stress may be influenced by exogenous agents of oxidative stress, radiation, trauma, drug activation, oxygen excess, or by exogenous oxidative stress which is associated with many pathological states including chronic inflammatory disorders, cardiovascular disease, injury to the central nervous system, and connective tissue damage. This and many other such aspects are presented clearly and in depth. The development of antioxidant drugs depends on the understanding of the mechanisms underlying the generation of excessive free radicals in vivo, the factors controlling their release and the site of their action. This excellent volume presents an up-to-date account of the current state of knowledge in these areas.

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Free Radical Damage and its Control
Language: en
Pages: 389
Authors: C.A. Rice-Evans, R.H. Burdon
Categories: Science
Type: BOOK - Published: 1994-02-09 - Publisher: Elsevier

This book provides a comprehensive treatise on the chemical and biochemical consequences of damaging free radical reactions, the implications for the pathogenesis of disease and how this might be controlled endogenously and by radical scavenging drugs. Oxidative stress may be influenced by exogenous agents of oxidative stress, radiation, trauma, drug
Brain Lipids and Disorders in Biological Psychiatry
Language: en
Pages: 173
Authors: E.R. Skinner
Categories: Medical
Type: BOOK - Published: 2002-03-07 - Publisher: Elsevier

Leading authorities examine the possible role of brain lipids in the development of conditions such as schizophrenia, depression, Alzheimer's disease and personality disorders and violence. A better understanding of the underlying causes of these debilitating medical disorders is of utmost importance and may contribute towards a means of prevention, amelioration
Biochemistry of Lipids, Lipoproteins and Membranes
Language: en
Pages: 607
Authors: Dennis E. Vance, J.E. Vance
Categories: Medical
Type: BOOK - Published: 2002-12-20 - Publisher: Elsevier

The first edition of this book was published in 1985. The content of the 4th edition reflects the enormous advances that have occurred since that time in the field of lipid biochemistry. This publication is unique in that it represents a bridge between the superficial coverage of the lipid field
Chromatin Structure and Dynamics
Language: en
Pages: 507
Authors: J. Zlatanova, S. H. Leuba
Categories: Science
Type: BOOK - Published: 2004 - Publisher: Gulf Professional Publishing

Biological processes that replicate, preserve and use the genetic information encoded in DNA must operate in the context of chromatin, a highly organized complex of DNA and proteins. These proteins do not merely package the DNA in the tiny volume of the nucleus, but impart the structure the ability to
Gene Transfer and Expression in Mammalian Cells
Language: en
Pages: 680
Authors: S.C. Makrides
Categories: Science
Type: BOOK - Published: 2003-11-07 - Publisher: Gulf Professional Publishing

The production of proteins in mammalian cells is an important tool in numerous scientific and commercial areas. For example, proteins for human therapy, vaccination or diagnostic applications are typically produced in mammalian cells. Gene cloning, protein engineering, biochemical and biophysical characterization of proteins also require the use of gene expression